LLRICE601 should not be approved for human consumption by the United States Department of Agriculture Animal and Plant Health Inspection Service (USDA APHIS) not least because the data submitted to APHIS by Bayer is woefully inadequate. The rice contains additional and unwanted gene sequences, derived from the imprecise method used to manipulate its genome. This means there could be compounds in the rice that indeed might be problematic for human health. Since the company did not provide comprehensive data there are good reasons for concern. The food safety of LLRICE601 is unknown.